Leonardo Dissects a Hundred-Year-Old Man
1503
In a Florence hospital, Leonardo da Vinci performed an autopsy on an old man who had died peacefully and discovered that his arteries were thickened and narrow. Leonardo's red-chalk drawings, four centuries before modern medicine, sketched the first anatomical account of atherosclerosis in history. His comparison with a child's organs constituted the first systematic study of age-related anatomical changes in medical history.
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